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D., Wei C

Although IN delivery of DFO appears to be well tolerated in animal models, repeated administration can potentially cause nasal irritation or epistaxis (nosebleed), which can induce inflammation or reduced drug uptake

Results P2-HNF4 expression was up-regulated in human metastatic GC samples By analyzing the mRNA expression data from three GC-related datasets, GSE54129, GSE63089 and GSE79973, in the Gene Expression Omnibus (GEO) database and those in the Cancer Genome Atlas (TCGA) database, we confirmed the overexpression of HNF4 in GC tissues as compared to normal gastric tissues (Fig

Stern et al., 2022