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Stop or pause if subjective improvement has plateaued, if the target injury has resolved, after the planned cycle length (typically 8 to 12 weeks), or if any adverse effects appear

But if your goal, as is the case in most dedicated research, is to explore the absolute maximum potential for tissue regeneration and recovery, the evidence strongly suggests that these two should be kept far apart

However, there may be enough information from the history and physical examination that an MRI is not need by an experienced physician

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