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J.WangJ

doi: 10.3945/an.114.007732 56

These inflammatory mediators also suppress hepatic production of SHBG, thereby elevating free androgen levels and worsening hyperandrogenism [2,18]

However, challenges such as the long-term survival and integration of transplanted cells within the hostile ALS microenvironment remain significant hurdles in preclinical models (60, 61)