Briefly, LFP, EEG, and EMG signals from the head mount were fed through a PCB-based preamplifier (Part #8406-SL, Pinnacle Technology, Inc., Lawrence, KS, USA) to a commutator (Part #8408, Pinnacle Technology, Inc.), which was read into a PC-based acquisition system (Pinnacle Technology, Inc
Main Research Findings 1) Epitalon administration was shown to act as a potentially epigenetic mechanism through the stimulation of gene expression and protein synthesis during neurogenesis
Activation of AMPK by upstream kinases phosphorylates target enzymes, such as acetyl-coA carboxylase (ACC), leading to inhibition of lipogenic pathways and activation of FA oxidation 22
Histopathological findings revealed preservation of neural architecture, with reduced axonal degeneration, diminished neuronal loss, and limited formation of cystic cavities, suggesting an attenuation of secondary injury processes (12)