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Generally well-tolerated with minimal reports of mild headaches or nasal irritation

While direct evidence for proprioceptive improvements remains limited, anecdotal reports from users with CAI often describe improved ankle awareness and reduced giving-way episodes

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We know that macrocytosis is a very, very late stage of B12 deficiency and that severely deficient patients may not present with this sign, the administration of folic acid also masks macrocytosis by normalising the size of the blood cells