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Akbar Khans physician, a Persian, saw that his king would cough during and after smoking tobacco from a pipe (the common method of smoking tobacco at the time), and so he invented the worlds first Hookah: a Waterpipe that that used a clay bowl, mounted onto a coconut shell filled with water and with a bamboo straw to draw in the smoke

However, most studies have compared e-cigarettes to placebo alone, or to nicotine replacement therapy, such as patches and lozenges, which help smokers manage their withdrawal symptoms

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Electronic nicotine delivery systems (ENDS) are also dangerous to leave in a childs reach, because a child may put the mouthpiece in their mouth