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Skin improvements are often visible within 28 days

This study was supported by National Key R&D Program of China (2023YFC2509100), Science and Technology Commission of Shanghai Municipality (23Y31900400), National Natural Science Foundation of China (82370984 & 82370980), Natural Science Foundation of Shanghai (22ZR1437600), Shanghai's Top Priority Research Center (2022ZZ01017), and Dominant disease biological sample project of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine (YBKA202201)

A mismatch between the breakdown rate of compounds in phase I and phase II can cause oxidative stress in the cells

Unconventional targeting of a thiol peroxidase to the mitochondrial intermembrane space facilitates oxidative protein folding