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Quitting smoking is so hard because of the complex interplay between physical addiction to nicotine and the psychological habits formed around tobacco use, as studied in an article by the Centers for Disease Control and Prevention titled Why Quitting Smoking Is Hard. Physically, nicotine creates dependence by altering brain chemistry, leading to withdrawal symptoms such as irritability, cravings, and anxiety when a person tries to quit

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Understanding its biological and other underpinnings "could lead not only to a better, clearer and balanced understanding of the Black experience," but to new approaches to treatment for everybody