Signs of histopathologic changes such as edema, vacuolar degeneration and pyknosis, and polymorphonucleated leukocyte (PMNL) infiltration were noted if present
Materials and Methods This study adhered to CONSORT guidelines and was approved by the Institutional Review Board at Nova Southeastern University in Fort Lauderdale, FL, USA
ROS exert cellular toxicity by modifying DNA, lipids, and proteins through DNA base oxidation, lipid peroxidation, and protein carbonylation (protein oxidation), respectively 7,8,9
Eur J Neurosci 12:37218, PMID: 11029642 Matsuzawa D, Obata T, Shirayama Y, Nonaka H, Kanazawa Y, Yoshitome E, Takanashi J, Matsuda T, Shimizu E, Ikehira H, Iyo M, Hashimoto K (2008) Negative correlation between brain glutathione level and negative symptoms in schizophrenia: a 3 T 1H-MRS study