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With that patented strain, 22nd Century subsequently created a series of very low nicotine content cigarette products called SPECTRUM that were exclusively provided to academic research institutions for use in clinical studies to assess the physiological and psychological effects of nicotine reduction in heavy smokers

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However, some of the industry has pointed out in their conversations with PipesMagazine.com that the cut requirements are too thick and the moisture content is too high to cover all legitimate pipe tobacco