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References Pouya Shafipour, MD, MS

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Some common phentermine withdrawal symptoms include: Fatigue or extreme tiredness Depression or mood changes Increased appetite Insomnia or sleep disturbances Irritability Anxiety Headaches Nausea or vomiting Cravings for the drug Generally, individuals will begin to feel initial symptoms like fatigue, increased appetite, and mood changes within 24 to 72 hours after stopping the medication