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For example, a minor increase in liver function enzymes in a rodent toxicology study, with no clear dose relationship, may not cause any undue concern if no associated macroscopic or microscopic changes in the liver are observed

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Role of carnitine The common mild elevation in aminotransferases is usually reversible when VPA therapy is discontinued or the dose reduced

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People with chronic inflammation and stress also often burn through magnesium more quickly, which is yet another reason why supplementation is a good idea

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effects in humans remain investigational, not established

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