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Another small, randomized, double-blind trial in 93 individuals with low vitamin D status found no additional benefit of B-vitamin supplementation (50 mg/day of vitamin B6, 0.5 mg/day of folic acid, and 0.5 mg/day of vitamin B 12 ) on markers of bone health over a one-year period beyond that associated with vitamin D and calcium supplementation

Assessing vitamin B12 absorption and bioavailability: Read the label

Findings suggest potential interactions with thymic and pineal pathways, with research pointing toward possible influences on systemic regulation, cellular differentiation, and lifespan markers