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doi: 10.1186/s13075-015-0539-z 80 LopezPRodriguez-CarrioJMartinez-ZapicoAPerez-AlvarezAILopez-MejiasRBenaventeLet al

GHK-Cu is a copper-binding peptide that has been studied for its role in wound healing, collagen production, and antioxidant activity

Versus near-zero through intact skin under identical conditions 3

Results Administration of exogenous melatonin alleviates allergic airways disease severity in allergen-exposed mice Given the growing evidence linking circadian disruption to increased severity of allergic asthma ( Alternaria alternata (AA) or PBS daily for four days, with or without concurrent intraperitoneal melatonin treatment using established protocols described previously ( Figure 1A )