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Mitogenic G(i) protein-MAP kinase signaling cascade in MC3T3-E1 osteogenic cells: activation by C-terminal pentapeptide of osteogenic growth peptide [OGP(10-14)] and attenuation of activation by cAMP

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NADPH-FSP1-CoQ10 pathway In the study of the ferroptosis-resistant cell line MCF7, the researchers screened the complementary gene for GPX4 deletion and found the apoptosis-inducing factor mitochondrial 2 (AIFM2) gene, which was initially found to induce apoptosis, and the researchers named it ferroptosis suppressor protein 1 (FSP1) [22]