pylori strain lacking the major Dsb oxidoreductase, encoded by hp0231 , is deficient in CagA translocation into host epithelial cells as Hp0231, among other activities, influences the structure of HopQ, an outer membrane protein that mediates pathogen adhesion to epithelial cells by interaction with CECAM receptors (Javaheri et al
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The finding that younger people with COVID-19 also are glutathione deficient and have elevated oxidative stress and oxidant damage is really surprising, because we do not normally see these defects in younger age groups
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