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10.1371/journal.pone.0093258 139 YingX.GaoK.LuoZ.RenY.ShenC.ZhangH.et al (2025)

Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer

For instance, genetic variations (polymorphisms) in GST genes are well-documented to influence an individuals susceptibility to certain diseases, their response to drug treatments, and their capacity to detoxify environmental toxins

Recent studies suggest that cancer cells are under increased oxidative stress caused by oncogenic transformation, leading to metabolic alterations that result in ROS production 56