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These concentrations make dosing calculations simple

However, in a much larger randomized controlled trial of simvastatin and an antioxidant combination of 600 mg of all - rac --tocopherol (297 mg of RRR --tocopherol), 250 mg of vitamin C, and 20 mg of -carotene daily) in more than 20,000 men and women with CHD or diabetes mellitus, the antioxidant combination did not adversely affect the cardioprotective effects of simvastatin therapy over a five-year period (131)

However, cyanide compounds produced during amygdalin decomposition caused important side effects when amygdalin was utilized (236) ( Table 2 )

304 , R553R565 (2013)