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8 Although folate deficiency may also produce a megaloblastic anemia, it is less common in the United States because of required folate fortification of enriched grain and cereal products

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Nevertheless, an internal consumption of B12 should have positive effects on skin diseases in certain cases probably due to the role of the vitamin in tackling nitrogen oxides

[17] While it technically refers to anemia caused specifically by autoimmune deficiency of intrinsic factor, it is commonly used to refer to B 12 -deficient anemia as a whole, regardless of cause