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In a clinical trial of AIDS patients were treated with 1.8 g/day of NAC for two weeks with the glutathione (GSH) status monitored in plasma and lymphocytes

Moreover, supplementation with Se could enhance the expression of GPX4 in follicular helper T cells and increase the number of helper T cells to improve the antibody responsiveness of immunized mice after vaccination [30], indicating that the regulation of Se on GPX4 plays an essential role in normal mammalian embryos

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