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15 These techniques could be useful in clinical practice, particularly applanation tonometry, as numerous studies have shown that increased arterial stiffness as measured by aortic pulse wave velocity (PWV) and augmentation index (AIx) is directly and independently associated with increased risk of cardiovascular complications and events

Nicotine gum in particular can cause very severe symptoms because they contain high amounts of nicotine and xylitol

Oviatt might be right to temper claims of a broader behavioural comeback

Methods In a six-week actual use study of an HTP (IQOS), adults in the United States, ages 2164 (n = 615), who smoke combustible cigarettes and were not planning to quit were offered free choice of HTPs (one non-menthol and two menthol varieties) to use ad libitum