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Based on this limited information we conclude the following points: Glutathione has positive effects on lighting the skin tone The effects of Glutathione as a skin-whitening agent havent been well established Glutathione capsules & creams may be effective (& reasonably safe) in skin-whiteninig, but long-term effects are still uncertain & unknown For Glutathione injections, we do not have sufficient safety information

6a), which could be partially rescued by YBX1 overexpression (Extended Data Fig

However, it is also questionable whether they can provide therapeutic benefit via antioxidant effect at these low concentrations