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It was proposed that disulfide formation alters catalytic efficiency by affecting the dynamic movements of the N-terminal loop (Ravilious et al., 2012)

Ethics All animal experimental protocols in this study were approved by the University of Zurich Animal Protection Office and Ethics committee, the Cantonal Veterinary Office of the Canton of Zurich (licences n 102/2018 and 136/2021), and conform to Swiss Animal Protection guidelines and regulations (Swiss Animal Protection and Swiss Animal Act and Ordinance) and in accordance with the EU Directive on the protection of animals used for scientific purposes

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