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Chen Y, Saari JT, Kang YJ

Its binding profile is deliberately imbalanced, showing strong affinity for the GIP receptor with an EC50 of 22.4 pM while demonstrating roughly five times weaker GLP-1 receptor activation compared to native GLP-1, with an EC50 of 934 pM versus 70.5 pM for the endogenous hormone

Batch: GF-NEPI20-B241 Key analytical results include: Assay Content: 22.6 mg Identification Retention Time: 0.991 Identification Spectrum: 994 Purity: greater than 99.8 percent Bacterial Endotoxins: below 0.001 EU per mg Total Aerobic Microbial Count: not detected Total Yeast and Mold Count: not detected Independent heavy metal screening confirmed no detectable levels of arsenic, cadmium, cobalt, lead, nickel, mercury or vanadium

- Va oral: biodisponibilidad considerablemente menor pero funcionalmente activa debido a actividad local en mucosa GI y posible absorcin peptdica intacta parcial va transportadores PepT1