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A single cigarette tar contains about 10 to 12 mg nicotine, and when a cigarette is smoked, between 1 and 2 mg is inhaled into the lungs [64]

Forty days later, the rabbits has tumours growing from their ears

In a set of studies demonstrating the role of TRPA1 in cough, Andre and colleagues established that both acrolein and crotonaldehyde induce robust coughing in guinea pigs, and that this effect could be inhibited by the selective TRPA1 antagonist HC-030031 (Andre et al., 2009)

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