Antioxidant defense via Nrf2 pathway activation Oxidative stress, the accumulation of reactive oxygen species that damage cells, mitochondria, and DNA, is a foundational driver of accelerated aging
For example, she says, its more common for people age 50-plus to take metformin, which is widely prescribed to lower blood sugar levels and manage type 2 diabetes
This approach will enable evaluation of tissue responses to various treatments, particularly for conditions like EC, where patient-specific organoids can help to identify the most effective chemo- or targeted therapy options [91, 92]
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