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Millions of people live with this chronic autoimmune condition, watching their skin cycle through painful flares and brief periods of calm

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Rats were assessed for fine motoric impairment with modified Irvine, Beatties and Bresnahan forelimb scale (IBB scale) that can detect recovery of both proximal and distal forelimb function including digit movements during a naturally occurring behavior that does not require extensive training or deprivation to enhance motivation (64)

Application frequency and timing Twice-daily application (morning and evening) produces optimal results for most users