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Amyloidogenic proteins then interact with cardiolipin in the outer membrane to induce an apoptotic cascade, resulting in neuronal cell death and, ultimately, neurodegenerative disease

Athletes often face strains, tears, or overuse injuries that can linger and worsen without proper intervention

Furthermore, memory deficits have been observed in animal models of diabetes [4] that show BBB impairment accompanying pericyte loss and neuronal dysfunction [5]

Cranwell WC, Lai VW, Photiou L, Meah N, Wall D, Rathnayake D, Joseph S, Chitreddy V, Gunatheesan S, Sindhu K, Sharma P, Green J, Eisman S, Yip L, Jones L, Sinclair R (2019) Treatment of alopecia areata: an Australian expert consensus statement