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Rare side effects are hypoglycemia, pancreatitis, diabetic retinopathy, gall bladder problems, gastroparesis (due to slowed gastric emptying), and increased risk of aspiration during sedation and anesthesia

doi:10.7860/JCDR/2016/18208.8127 If a good first response is seen, a second injection may be considered when the improvement from the first injection begins to taper off

Improves Mood: Some people report improved mood and mental clarity with B12 supplementation

Absorption of vitamin b12 The guts ability to absorb vitamin b12 can be reduced by a number of factors, these include Some conditions of the digestive system, such as Chrons disease