Paulas Choice
Concomitantly, water influx causes matrix swelling, rupture of the rigid OMM and release of apoptogenic proteins sequestered in IMS although, apoptotic cell death under MPT is inhibited due to energetic failure and ATP exhaustion and oxidative stress-mediated caspase inactivation
The important caveat is that all of them come from in vitro cell studies or animal models not human beings
doi: 10.1016/j.hbpd.2022.08.004 Summary Keywords pulsed electric fields, cancer, irreversible electroporation, immunotherapy, mechanism of action, clinical prospects Citation Zhang L, Dong S, Teng F, Wang Y, Xu W, Chen Y, Yu L, Yao C and Wang Z (2025) Pulsed electric fields: a sharp sword in the battle against cancers