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The other B12-requiring enzyme is methionine synthase as described in the the Amino Acid Biosynthesis page

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[8] Although not an absolute contraindication, patients with coronary artery disease or unstable angina should only use B-Complex injections containing niacinamide under physician supervision, since high-dose niacin supplements have been linked to arrhythmias in such patients

[283] Schwarzenegger believes that quality school opportunities should be made available to children who might not normally be able to access them