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Phenotypic Screening Deconvolution After a phenotypic screen identifies active compounds, metabolic fingerprinting provides the first mechanistic triage layer separating compounds that act through energy metabolism, membrane disruption, nucleotide biosynthesis, or signalling pathway inhibition without requiring individual target binding assays

This approach may be particularly valuable in studies examining how different signaling systems overlap during regeneration and structural remodeling

Effect of cannabis in combination with antidepressant drugs Figure 4C demonstrates the rearing activity in mice following cannabis treatment in combination with antidepressant drugs

The lancet Diabetes & endocrinology