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The red, scaly patches can be painful and itchy, and they can also lead to embarrassment and low self-esteem

IBD is marked by chronic inflammation of the GI tract and is associated with dysbiosisan imbalance between the guts aerobic and anaerobic bacterial communities

Myeloproliferative Disorders: Conditions like polycythaemia vera could be associated with increased B12 binding proteins, leading to higher circulating B12 levels 3 , 10 , 11

Notably, we generated various N-terminal truncation constructs for SnCE1, i.e., SnCE1 74-310 , SnCE1 85-310 , SnCE1 95-310 and SnCE1 104-310 , the catalytically inactive mutant SnCE1 C256A and the reported gatekeeper mutant SnCE1 W191A (Fig