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Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells

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I am not convinced the data is fully there yet. Tatem said he expects the hearings to be a hard-fought battle, but hopes committee members will consider what he described as real-world data from tens of millions of doses administered between 2014 and 2023

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