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However, they also pointed out that this explanation is not unarguable due to the fact that EDs are often consumed along with alcohol or used in circumstances inherently associated with increased adrenergic stimulation (e.g., playing sports, excessive work-related physical exertion, or during social gatherings) and these factors may also contribute to AE development [70]

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Additionally, a small subset of sensitive peptides may degrade more rapidly in alcohol-containing solutions, although this is rare