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Metabolic interaction: tumor-derived lactate inhibiting Cd8(+) T cell cytotoxicity in a novel route

It is a classic example of chicken or egg in which each persons root cause(s) differ from the next

This addresses the vascular component of nerve damage that is particularly relevant in diabetic neuropathy where microangiopathy starves nerves of oxygen and nutrients

What were building Neurophorol to enable (research-stage endpoints): receptor/pathway profiling + SAR learning neuroimmune and inflammation readouts oxidative stress / resilience markers reproducible preclinical validation workflows Were opening collaboration discussions with teams who can help validate and translate this platform responsibly: (Universities, Biotech companies, Tribal communities, and Investors) CB1/CB2 functional assays + signaling bias analytical chemistry (LCMS/NMR) + stability profiling neuroimmune models (microglia), biomarkers, preclinical design ADME/PK and translational study frameworks If you work in this space, comment NEUROPHOROL or DM your capability stack