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The blood selenium level of cancer patients is lower than normal, and the cancer mortality rate is also negatively correlated with the blood selenium level ( Epidemiological studies also suggest that the blood selenium concentration of people affected by diet and geological environment negatively correlates with the incidence and mortality of malignant tumors

Detection of GSH, ROS, and cleaved caspase-3/7 GSH/GSSG, GSH, ROS, and apoptosis were detected using the GSH/GSSG-Glo Assay (Promega, V6611), the GSH-Glo Assay (Promega, V6911), the ROS-Glo H 2 O 2 Assay (Promega, G8820), and the Caspase-Glo 3/7 Assay (Promega, G8091), respectively

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Molecular interaction studies