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Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Abbreviations A: Amyloid-Beta AD: Alzheimers disease ALA: Alpha-Lipoic Acid AMPK: AMP-activated protein kinase APP: Amyloid Precursor Protein AOPP: Advanced Oxidation Protein Products ATP: Adenosine Triphosphate BACE1: Beta-Site APP-Cleaving Enzyme 1 BBB: Blood-Brain Barrier CAT: Catalase CNS: Central Nervous System CoQ10: Coenzyme Q10 COPD: Chronic Obstructive Pulmonary Disease Cu 2* : Copper Ion DMTs: Disease-Modifying Therapies DNA: Deoxyribonucleic Acid DJ-1: Parkinsonism Associated Deglycase ETC: Electron Transport Chain Fe 2* : Ferrous Ion GABA: Gamma-Aminobutyric Acid GAPDH: Glyceraldehyde 3-Phosphate Dehydrogenase GPx: Glutathione Peroxidase GSH: Reduced Glutathione GSSG: Oxidized Glutathione H 2 0 2 : Hydrogen Peroxide HAP-1: Huntingtin-Associated Protein 1 HD: Huntingtons Disease Htt: Huntingtin IFN-: Interferon-gamma IL-17: Interleukin-17 IL-6: Interleukin-6 IV: Intravenous MAO: Monoamine Oxidase mHTT: Mutant Huntingtin MHC: Major Histocompatibility Complex MRI: Magnetic Resonance Imaging MS: Multiple Sclerosis mtDNA: Mitochondrial DNA NAC: N-Acetylcysteine NADPH: Nicotinamide Adenine Dinucleotide Phosphate NF-B: Nuclear Factor Kappa-light-chain-enhancer of Activated B cells NOX: NADPH Oxidase Nrf2: Nuclear Factor Erythroid 2-Related Factor 2 O 2 : Superoxide Anion OH : Hydroxyl Radical OS: Oxidative stress PD: Parkinsons Disease PEG: Polyethylene Glycol PGC-1: Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Prx: Peroxiredoxins PUFAs: Polyunsaturated Fatty Acids RNAi: RNA interference ROS: Reactive oxygen species SOD: Superoxide Dismutase SOD1: Cu-Zn Superoxide Dismutase SOD2: Mn Superoxide Dismutase SOD3: Extracellular Superoxide Dismutase TLR: Toll-Like Receptor TNF-: Tumor Necrosis Factor-alpha Trx: Thioredoxin UV: Ultraviolet 4-HNE: 4-Hydroxynonenal 8-oxoG: 8-oxoguanine References 10 Early Signs and Symptoms of Alzheimers & Dementia | alz.org [WWW Document], n.d