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Fully achieved reduction of severe lesions in the brain, heart, lungs, liver, kidneys, and gastrointestinal tract reduced thrombosis in both veins and arteries, peripherally and centrally, and fully abrogated intracranial (superior sagittal sinus), portal, and caval hypertension and aortal hypotension may be regarded as a proof of concept

Free Radic Biol Med 199:97112

Additionally, GO can interact at the genetic level, potentially binding to DNA and causing genetic alterations, which further highlights the importance of thorough toxicological studies

Our structural analysis indicates that there are three equivalent Chc boxes for adaptors present in yeast NTD