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Systematic analysis of the molecular mechanisms mediated by coffee in Parkinson's disease based on network pharmacology approach

PMID: 4027754

Otx2, a developmental homeoprotein (HP), plays a crucial role in regulating visual cortex plasticity throughout the embryonic, postnatal, and adult stages ( Here, we have developed two chimeric peptides, namely, RGD-GHK and sOtx2-GHK, composed of an integrin v3-binding or a glycosaminoglycan (GAG)-binding peptide to enhance the specific cell-binding effect, along with GHK for skincare

Especially in brain tumors, the changes in endothelial gene expression induced by the tumor microenvironment can also be beneficial for therapy