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Under the joint regulation of existing mitochondrial nuclear DNA (nDNA) and mitochondrial DNA (mtDNA), new mitochondria are synthesized to replace damaged mitochondria, so as to repair mitochondrial structure, maintain mitochondrial function, increase antioxidant effect, reduce pathological oxidative stress and promote ATP production to meet the metabolic needs of eukaryotic cells under physiological and pathological conditions (Ferreira et al., 2019

These metabolic changes are consistent with recent reports linking endothelial dysfunction and metabolic syndrome to SSHL pathophysiology, as described by Cavallaro et al

They're particularly celebrated for their ability to: Boost collagen and elastin production naturally, essential for reducing the appearance of fine lines and wrinkles

Oncogene 27 , 69306938 (2008)