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Together, these results suggest that the dramatically increased EC 50 of vitamin K for VKD carboxylation in DKO cells results from the cells losing the ability to recycle K epo by VKOR, supporting the essential role of VKOR in VKD carboxylation as previously reported 24,25,26

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Gmez-ManzoSTerrn-HernndezJDe la Mora-De la MoraIGonzlez-ValdezAMarcial-QuinoJGarca-TorresIet alThe stability of G6PD is affected by mutations with different clinical phenotypes