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As an example, lets take a look at one of the most popular indexes: the S&P 500

In a meta-analysis that investigated the causes of poor acute postoperative pain control based on 33 clinical studies, preoperative smoking was an independent predictor [65]

You start to compromise even the basic, original intent

Stem bore dating is not, however, generally used by European archaeologists since it requires a large sample and a lot of work to produce a single date, which does not provide a very sensitive means of assessing either the duration of occupation on a given site or fluctuations of finds use/deposition within that span