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Also, it was shown that dietary quercetin mitigates the metastasis-promoting effects of disrupted light-dark cycles, suggesting that holistic dietary or chrono-modulated interventions may offer therapeutic benefit in circadian-compromised oncologic contexts 59

[1] In the SURMOUNT-1 clinical trial, higher doses in non-diabetic adults demonstrated significant weight loss, with participants losing approximately 15-20% of body weight over 72 weeks

Without this process, wed still be treating headaches with leeches (yikes)