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Glutathione has become something of a buzzword in the health and wellness space in recent years, and for good reason
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These IR-induced mitochondrial defects are evident in both insulin-sensitive tissues (liver, muscle) and in the heart and brain, providing a mechanistic link between metabolic dysfunction and cardiovascularcognitive comorbidity
On the basis of such standard assays, different isoforms are hereinafter referred to as enzymatically active or inactive glutaredoxins for the sake of simplicity (without excluding the possibility that inactive isoforms might actually catalyse other reactions with specialized substrates in vivo )
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