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The result is a dual boon: reduced excitotoxicity and dampened neuroinflammation, though at the cost of impairing astrocyte-to-neuron metabolic support

J Med Plants Res 1(5):095102 Alten R, Gomez-Reino J, Durez P, Beaulieu A, Sebba A, Krammer G, Preiss R, Arulmani U, Widmer A, Gitton X, Kellner H (2011) Efficacy and safety of the human anti-IL-1beta monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, Phase II, dose-finding study

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