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While ROS generation is a natural part of cellular metabolism, the balance between ROS production and antioxidant defenses is key to preventing oxidative stress and ensuring proper cellular function 54

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Why: Degradation may not be visible

The phenylarsenoxide group is the active moiety, imparting to GSAO its activity by crosslinking closely spaced protein thiols and forming a high affinity ring structure between its arsenic and the thiols ( FIGURE 3 4-( N -( S -glutathionylacetyl)amino)phenylarsonous acid in its original form is essentially membrane impermeable