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Monitoring and follow-up should continue as recommended for tirzepatide therapy, typically including assessment of glycemic control (A1C), weight, gastrointestinal tolerability, and screening for potential adverse effects

See Example Case 3 the individual did not improve using the commonly known intermediates and support supplements of the methionine cycle such as B12 (cyanocobalamin) by injection, folic acid, betaine, SAMe, N-acetylcysteine, and even glutathione in the neat form (not in the form claimed in the present invention)

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