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One 8-week study (n = 13) found a large effect size (d = 1.616) in reducing repetitive behaviors, as measured by the C-YBOCS (185), while a 12-week trial (n = 27) showed significant improvement in irritability on the Aberrant Behavior Checklist-Irritability subscale and Clinical Global Impression-Improvement scale (186)

There are not yet significant clinical trials for these peptides, but some doctors, patients, wellness influencers, and Kennedy have voiced support for opening up the market for these drugs

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For any in-vivo animal research conducted in the United Kingdom, full compliance with the Animals (Scientific Procedures) Act 1986 (ASPA) is mandatory, requiring valid Home Office licences and institutional ethical approval