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For instance, food-based dietary guidelines could be updated to include specific, mechanism-aware advice, such as recommending one serving of cruciferous vegetables three to four times per week to leverage Nrf2 activation, or promoting the inclusion of fermented foods like yogurt or kimchi to support gut health via microbial metabolites

More recently, focus has been on psoriasis as an IL-23/Th17-mediated disease, with therapies including anti-IL-12/23 subunit p40, anti-IL-17, and anti-IL-23p19 monoclonal antibodies

Awamleh, Z., Gloor, G

For that reason, many patients try to avoid Accutane, and many doctors view it as a treatment of last resort